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Best CBD Vape Juice in 2023 – Top 5 E-Liquids & Juices Reviewed

CBD can help relieve inflammation, ease pain, and calm an anxious mind.

Presented by Originated Media February 23, 2023

CBD can help relieve inflammation, ease pain, and calm an anxious mind. There are many ways to enjoy it, from oral tinctures to topical gels. One common, fast-acting CBD product is CBD vape juice. These tasty juices are easy to vaporize and inhale, giving you quick relief from whatever ails you.

Most CBD companies now offer at least a few different CBD vape products, but with so many options for vaping CBD to consider, it’s not easy to select the best CBD vape juice for your needs. That’s why we created this list. We combed the market, did our research, and settled on five brands that we believe offer the most incredible CBD vape juices.

Our Top 5 CBD Vape Juices

  1. CBDfx: Best All-Around CBD Vape Juices
  2. Koi CBD: Best Flavor Choices
  3. Diamond CBD: Best for Variety
  4. Secret Nature: Best for Natural Hemp CBD Vapes
  5. Just CBD: Best for Range of Potencies

The best CBD brands share a few common traits: They source their ingredients responsibly, lab-test their products, and receive rave reviews from customers. Beyond that, each CBD brand has something unique to offer, especially when it comes to their vape products. Whether you’re new to CBD or an experienced user, we’re confident you’ll love the CBD vape juice choices these five top brands have crafted.

5 Best CBD Vape Juice Options - Reviews

1. CBDfx: Best All-Around CBD Vape Juices

CBDfx is a California-based CBD company that has a keen interest in educating the public about hemp and CBD products. They are a member of the National Hemp Association, U.S. Hemp Roundtable, and California Hemp Council. All of their products are backed by a 60-day guarantee, and they use the latest carbon dioxide extraction methods to extract the CBD from hemp flowers.

There are a lot of great things to say about CBDfx, but we were especially impressed by their wide selection of CBD vape juices, or vape oils. Their standard, CBD Vape Juice comes in delicious flavors including Wild Watermelon, Strawberry Milk, and Fresh Mint. Customers can choose between 500 mg, 1000 mg, and 2000 mg potencies. 

CBDfx also has a line of CBD Terpene Vape Liquids, which contain higher levels of hemp terpenes for enhanced effectiveness. These CBD vape oils come in 500 mg and 1000 mg formulas, with flavor options including Gelato and Platinum Rose. 

Customer Opinions:

Customers find that CBD vape oils from CBDfx produce dense, fluffy clouds. The CBD takes action quickly, and the flavors are delicious. Reviewers mention using these CBD products for everything from headaches to depression, and with good results.


  • Huge selection of flavors and potencies
  • Certified Cruelty-Free
  • Made with a 50/50 ratio of vegetable glycerine (VG) and propylene glycol (PG)
  • Full-spectrum and CBD isolate options
  • Flavored with food-grade ingredients


  • 2000 mg formula only comes in small bottles

CBDfx vape liquid products are perfect for new CBD users who want a tasty vaping experience. The stronger formulas are a great choice for those seeking relief from chronic pain, anxiety, or PTSD symptoms.

Learn more at CBDfx.com

2. Koi CBD: Best Flavor Choices

Koi CBD has been in business since 2015, giving them plenty of time to perfect their formulas. They’re a member of the U.S.Hemp Roundtable and Hemp Industries Association, and they’re working to clear some of the confusion around CBD while advocating for responsible hemp plant farming and CBD extraction. 

Koi CBD vape juices are all made with USA-grown hemp. They’re lab tested for purity and potency, and customers can see the full panel analysis results on their website. We were especially impressed with the flavors offered. Vanilla Caramel Custard is sweet and almost creamy. It comes in 250 mg, 500 mg, and 1000 mg formulas. Other top CBD vape oil flavors include Lemon-Lime, Tropical Popsicle, Blue Raspberry Dragon Fruit, and Peppermint. Customers report barely any hemp aftertaste with these potently flavored vape juices.

Customer Opinions

Reviewers who are first-time users of CBD tend to like the 250 mg formulas from Koi CBD. They contain just enough CBD to give you relief without overdoing it. Customers also rave about the dropper bottles, which are convenient to use and designed to prevent spills.


  • Multiple potencies
  • Huge flavor selection
  • Tested for more than 100 potential contaminants
  • Flavors can be mixed for a custom experience


  • May contain legally compliant traces of THC

Koi CBD is great for anyone who wants to branch out from typical CBD vape juice flavors. The convenient dropper bottles make it easy to fill even the smallest of vape pens.

Learn more at KoiCBD.com

3. Diamond CBD: Best for Variety

Every once in a while, you come across a product that you just need to try for yourself. That was how our editors felt when they found Diamond CBD vape juices. This company is well-deserving of a spot on our best CBD vape oil list. They coordinate with doctors and scientists to develop some of the purest, most potent CBD products on the market. Diamond CBD also includes lots of details on their labels, so you know exactly what you are buying.

Diamond CBD sells their vape juices in bottles, but also pre-loaded into disposable cartridges. One favorite is their Blue Dream Cartridge, which contains 800 mg active CBD. Customers also love the Strawberry Cough Cartridge. Its powerful blend of CBD and terpenes leaves you feeling relaxed and at-ease. Lab reports for the CBD vape liquid products are available on the company’s website, and you get approximately 240 puffs per cartridge.

Customer Opinions

Many reviewers use Diamond CBD products to help them sleep. They report needing only one or two puffs of the vape juice to relax their body and mind. Most customers find the flavors appealing, although some of the fruitier flavors are very sweet.


  • Cartridge and bottle options
  • Multiple flavors and potencies
  • Lab-tested for purity and potency
  • Clear, concise labeling


  • Some products are on the expensive side

Since Diamond CBD has so many vape products, they’re a good supplier for almost any CBD user to consider. Their disposable vapes are perfect for those who don’t want to invest in an expensive, reusable vape pen. 

Learn more at DiamondCBD.com

4. Secret Nature: Best for Natural Hemp CBD Vapes

There are a lot of things to love about Secret Nature CBD vape juices. First, this company makes all of their CBD vape liquid products in small batches. They also use fresh, live resin, which means you always get the benefits of terpenes and additional cannabinoids in the hemp. While Secret Nature’s CBD vape liquids are not heavily flavored, they do have a very pleasant, light hemp taste that appeals to many more experienced CBD users.

Secret Nature offers CBD vape juices derived from various strains of hemp. The Gelato 33 is a hybrid strain good for daytime balance and relaxation. Another favorite is the Forbidden Fruit, an indica strain that will help you relax and drift off to sleep in the evening. Bellini, a sativa strain, would be good for relieving pain and inflammation when you don’t want to feel drowsy.

Secret Nature has been growing hemp for over a decade, and their experience shows in the quality of their products. All of their CBD vape juice is derived from indoor-grown hemp and contains <0.3% THC as required by law.

Customer Opinions

Customers report many of these CBD vape oil products have a natural hemp flavor. They produce large, dense clouds of vapor, and the CBD takes effect quickly in the body. Customers find Secret Nature products effective for pain relief, sleep, and mood control.


  • Terpene-heavy formulas made from various strains
  • Clear, informative labeling
  • Lab-tested for purity and potency
  • Many full-spectrum options


  • Natural hemp flavor does not appeal to everyone

If you’re looking for CBD vape juice that is as natural as can be with the minimum amount of CBD vape additives required and no added flavorings or colorings, Secret Nature is a good brand to consider. Their strongest CBD vapes are good for pain relief and inflammation control.

Learn more at SecretNatureCBD.com

5. Just CBD: Best for Range of Potencies

Just CBD keeps things simple, but they focus on the important details, resulting in truly top-quality CBD products. The company was founded in 2017. All of their products are made in the U.S., and they’re members of the Florida Hemp Council. 

Just CBD works with medical advisors to develop their products, and they comply with the strictest of standards when it comes to farming and testing practices. While they are particularly well known for their CBD gummies, their CBD vape juices have quite a loyal fan base, too.


Just CBD offers their CBD vape liquid options in 8 different flavors: Pineapple Express, Watermelon OG, Blue Dream, Blue Razz, Strawberry Cheesecake, Cookies, Mango Ice, and Pina Colada Ice. Choose between 100 mg, 250 mg, 500 mg, 1000 mg, 1500 mg, and 3000 mg potencies. There is truly something for everyone, from the new user who wants mild relaxation to the migraine patient who needs super-strong relief.

Customer Opinions

Customers love the flavors of Just CBD vape juice. The Mango Ice and Pina Colada Ice, especially, get rave reviews. The 100 mg bottles are beloved by new CBD users and those who are more sensitive to CBD.


  • Incredible selection of flavors and potencies
  • Lab-tested for purity and potency
  • High-VG formulas for enjoyable vapor
  • Convenient, no-mess dropper bottles


  • Some reviewers find the flavors too sweet

Just CBD vape juices are a good choice for anyone who prefers flavored CBD vape liquids. If you are looking for a less potent CBD product, the 100 mg bottles are perfect.

Learn more at JustCBDStore.com

How We Picked These Top CBD Vape Oil Options

With so many different companies selling CBD vape juice, we really wanted to make sure the ones we listed here were the best of the best CBD vape oils. The ideal way to do that, we decided, was via a two-stage process. The first step of the process was narrowing down our options to companies that met the following criteria:

Lab Testing: There were actually two types of testing we wanted to see. The first was testing for potency. This type of test indicates how much CBD is actually in the product. The second was testing for purity. This type of test ensures the CBD vape juice does not contain any harmful compounds such as pesticides or heavy metals. 

All of the companies on this list not only lab test their products, but also make those test results readily available to customers.

USA-Sourced Hemp: The best CBD companies, we found, were very particular about where they got their hemp from. All of the companies listed above extract their CBD from hemp grown in the U.S. Some companies grow their own hemp, and others source it from nearby farms that they trust.

Safe Additives: Because CBD vape juice is inhaled, the CBD vape additives, or carrier components, need to be safe and healthy. The companies on this list use vegetable glycerine and propylene glycol in their vape juices. Both of these ingredients are easy on the lungs.

Once we had a short list of companies whose vape oils met the criteria above, we started looking at the products in more detail. We favored companies that offered more than one variety of vape juice. After all, different customers have different dosing needs. Having multiple flavor options also makes vaping CBD a more enjoyable experience.

We read a lot of reviews as we compiled this list, too. Some of the questions we asked ourselves as we read the reviews included:

  • What symptoms do customers who use this vape liquid want to treat?
  • What do customers say about the packaging or bottle?
  • Do customers feel this product is clearly labeled?
  • Do customers like the flavors this product comes in?

Before long, it was clear that we had a few front-runners. These companies, which you see described above, truly offer the best CBD vape juice around. 

What to Consider When Buying CBD Vape Oils

CBD vape juice gives you a convenient way to enjoy the benefits of CBD on-the-go. You can enjoy one puff, or you can take several puffs for greater relief. But which CBD vape juice is right for you? Here are some key things to consider when selecting a brand and product.


Liquid CBD products are typically labeled with the number of mg of CBD the entire bottle contains. So, if you see a bottle of CBD vape juice that says “500 mg”, there is 500 mg of CBD in the whole bottle. If two bottles are the same volume, the one that contains the larger amount of CBD is more potent. For instance, a 500 mg bottle of CBD vape oil is more potent than a 250 mg bottle.

If you are brand new to CBD, then look for a less-potent vape juice. A 200 mg or 250 mg formula would be perfect. This allows you to enjoy a small dose of CBD with one puff, and then take additional puffs, if needed. If you find that you need to take multiple puffs of this low-potency CBD to get relief, then you can buy a more potent formula the next time.

If you are using CBD for chronic pain, anxiety attacks, or insomnia, then look for a more potent formula, such as a 2000 mg formula. These conditions often take higher doses of CBD to manage. A high-potency formula will allow you to get relief with just a few puffs.


Some CBD vape juices do not contain any flavoring; they taste naturally of hemp oil. Some CBD and hemp “purists” prefer this natural flavor.If you don’t love the flavor of hemp, look for a more creative flavor that sounds appealing. If you’d eat candy in that flavor, then you’d probably like CBD vapes in that flavor, too.

Full-Spectrum Versus CBD Isolate

Some vape juices are labeled “full spectrum CBD”. Others are made with CBD isolate. It’s important to know the difference between the two as you shop. 

Vape juices made with CBD isolate contain only CBD as an active ingredient. All other components of the hemp extract have been removed.

Vape juices made with full-spectrum CBD oil also contain other compounds from the hemp. These compounds may be other beneficial cannabinoids, like CBG and CBN. They may also be terpenes, which are aromatic flavor compounds. Terpenes affect the flavor of the CBD oil product, but they also have some therapeutic qualities. For example, myrcene supports relaxation and sleep. Linalool, another hemp terpene, is known for its stress-relieving qualities.

If you want a stronger, more noticeable effect from your vape juice, a full-spectrum product is often best. However, some full-spectrum products contain tiny traces of THC. If you’re concerned about this, then a CBD isolate product is a better choice.

Hemp Strain

Some companies that sell CBD vape juice list the strain of hemp that the CBD was derived from. This really only matters when you’re buying a full-spectrum CBD oil vape product.

Different strains contain different amounts of various terpenes and accessory cannabinoids, so they can have somewhat different effects when you take them. There are many hemp strains, but they generally fall into three categories:

  • Indica: These strains tend to be really relaxing and are good for evening use.
  • Sativa: These strains are less relaxing and are better for daytime use.
  • Hybrid: These strains are relaxing, but not overly so, and offer a good balance of benefits.

Bottle Design

Also pay attention to how the bottle holding the CBD vape juice is designed. This is largely a matter of preference. Some vape juices come in squeeze bottles that you simply turn upside down and empty into your vape pen. Other vape juices come with droppers, which you can use to dispense the CBD liquid into your vape pen. 


Does the company you’re thinking of buying from offer any sort of guarantee on their products? The companies listed above do. This sort of guarantee demonstrates that the company stands behind their products and has customers’ backs.

How Long Does CBD Vape Juice Stay in Your System?

Everyone metabolizes CBD at a different rate. So, it may stay in your system longer or for less time than it stays in a friend’s system. In general, however, the effects of CBD last anywhere from 2 to 6 hours. However, there will be some CBD present in your system long after this. 

The half-life of CBD is about 24 hours. That means that after a day, you have half the CBD you took still in your body. After two days, you have one quarter of the original dose still in your body.

There are several factors that affect how long CBD vape juice lasts for you.

  • Sex: Men tend to process CBD faster. It stays in women’s systems longer than in men’s systems. 
  • Diet: If you take CBD on an empty stomach, you will process and excrete it more quickly than if you were to take it with a meal.
  • Frequency of Use: CBD tends to build up in your system as you use it. The more often you take CBD, the longer your body will take to fully eliminate it.

When you first start using CBD vape juice, it’s a good idea to figure out how long it lasts for you. Take a dose, whether that is one puff or several. Then, every hour, check in as to how you are feeling. Make a note in a journal. When you are no longer feeling the effects, check how many hours it has been. That is how often you should take your CBD if you want sustained relief.

Potential Side Effects of CBD

CBD is generally well tolerated, whether you use it in vapor form or orally via CBD oils or edibles. There are some people who should not take it, however. CBD can react with certain blood thinning medications, so if you’re taking any of these meds, check with your doctor before adding CBD to your routine. Pregnant women and children should also avoid CBD unless it is prescribed by their doctor.

The average person will only experience CBD side effects if they take more CBD than is needed. These are the most common side effects.


The drowsiness that comes with CBD can be considered a benefit in the evening if you want to vape CBD to help you sleep. In the daytime, though, this can be considered a side effect. If the CBD vape juice is making you more drowsy than you’d like, try using a little less. For instance, try taking just one puff rather than two. You may also want to switch to a vape juice made with CBD isolate rather than full-spectrum CBD oil. Or, if you want to stick with full-spectrum products, look for one made from a sativa hemp strain, which tends to be more energizing. 

Dry Mouth

Dry mouth is common among CBD vape juice users. This is because of the interaction of CBD with certain cannabinoid receptors on your salivary glands. Dry mouth can cause dental problems over time, so if you are vaping CBD often, it’s important to find a way to manage this dryness. Some people chew sugar-free gum, which helps stimulate saliva production. You could also use a special toothpaste for dry mouth. 

Reduced Appetite

Some people find that they feel less hungry when using CBD. If you’re trying to lose weight, this may be a benefit, but in other situations, it can be an unwanted side effect. If CBD suppresses your appetite and it’s not one of the benefits of CBD that you’re looking for, try switching to a different strain. Some people find sativa strains are less apt to have this effect. You can also vape CBD only after you’ve already eaten a good meal.


1. What is the difference between CBD vape oil and CBD oil?

CBD oil and CBD oil tinctures are both products sold for oral use. You drop these products into your mouth and swallow them. CBD vape juice is specifically formulated to be turned into a vapor and inhaled. There may be CBD oil in the base, but CBD vape juice is made with vegetable glycerine and propylene glycol, both of which transform the CBD base into vapor which is safe and easy on the lungs when breathed in.

You should never vape CBD oil or tincture. Vaping CBD oil is highly discouraged because CBD oils and tinctures are not designed to be inhaled and could cause lung irritation. 

2. Can you swallow CBD vape oil?

Technically nothing bad would happen to you if you were to ingest CBD vape juice. However, these products are not formulated for oral use. They may not be absorbed very well in your digestive tract, and they may even cause some mild stomach upset. If you would rather take CBD orally, then look for CBD oils, CBD oil tinctures, or CBD gummies instead of vape juice.

3. How do you use CBD vape juice?

To use CBD vape juice, you first need to load it into your vaporizer. Usually, you do this by unscrewing the vape pen to reveal the refillable holding tank. Squeeze the CBD vape juice into the holding tank until it is nearly full. Check your vaporizer’s package or included instructions to determine exactly how full you should fill it. Then, close the unit up properly. You may need to twist it back together or tighten a fastener.

When your vaporizer is full and properly assembled, put the end in your mouth. Depending on the model, you may need to press a button to turn the unit on. Or, you may need to hold a button down as you inhale. In either case, make sure you inhale deeply to fully bring the CBD vapor into your lungs. Then, exhale slowly, enjoying the flavor of the vape. 

You should feel the effects of the CBD within a few minutes. If the effects are not strong enough, then you can take a second puff. In some cases, you may even need a third puff to get sustained, substantial relief.

4. What is full-spectrum CBD?

Full-spectrum CBD products are made with hemp oil that has not had any of its beneficial compounds removed. So, these products do not just contain CBD; they also contain other cannabinoids and terpenes. Although these other compounds are not as well studied as CBD, they are thought to have various beneficial effects in the body. Some examples of cannabinoids often found in full-spectrum products are:

  • CBN: This cannabinoid is really relaxing. CBD vape juice high in CBN is often a good choice for nighttime use.
  • CBG: This cannabinoid is good at enhancing pleasure and easing pain. CBD products high in CBG are good for people with arthritis and other chronic pain conditions.
  • CBC: This cannabinoid is also good for pain relief and is thought to have neuroprotective properties.

Most full-spectrum products also contain traces of THC. Note that this is legal, so long as the product contains less than 0.3% THC by weight. THC is a psychoactive compound, but the amount found in legally compliant CBD products is not enough to make you feel high.

5. What are terpenes?

Terpenes are the compounds that give the hemp plant — and other plants — their scent. If you smell a CBD product and think “wow, that smells like hemp”, it’s terpenes that you are smelling.

Research suggests that some of these terpenes actually enhance the effects and benefits of CBD. Here are a few examples:

  • Myrcene: This terpene smells like musk with hints of clove. It has relaxing properties and is also an antioxidant.
  • Linalool: This terpene smells like lavender. It helps relieve stress and support the immune system.
  • Pinene: This terpene, as the name suggests, smells like pine. It boosts mental alertness.
  • Limonene: This terpene has a citrus-like scent. It relieves stress and supports a healthy mood.

6. Can you overdose on CBD?

Researchers have yet to find a lethal dose of CBD. However, that does not mean you cannot take too much. A “toxic” dose of CBD has been identified: 20,000 mg. Even so, this toxic dose is not deadly. It simply causes a lot of unpleasant symptoms including diarrhea, exhaustion, and disorientation. 

Note that this toxic dose of CBD is too large for you to take on accident. A dose of 20,000 mg of CBD is the equivalent of 20x 1000 mg bottles of CBD vape juice. You would not be able to vape that much in a day if you tried!

Sometimes, people do take a little too much CBD. This causes milder side effects like tiredness and an upset stomach. The symptoms should go away within a few hours once the excess CBD leaves your system.

Final Thoughts

If you are looking for a way to get nearly instant relief from CBD, then CBD vape juice is well worth trying. You can take a puff or two of these products and experience pain relief, relaxation, and relief within minutes. The process of vaping CBD can also be enjoyable, thanks to the many flavors of CBD vape juice sold by reputable companies.

Just make sure you do your research and buy your CBD vape juice from a good supplier. All five of the companies we’ve featured above are excellent choices. If you’re new to CBD, start with a less potent product, and work your way up from there. Before long, you’ll have the hang of vaping, and you’ll look forward to trying new and different products for enhanced relief. The world of CBD is vast but enjoyable, and all are welcome.