Best CBD Creams of 2025: Top 5 Brands for Pain & Inflammation

If you struggle with chronic pain or inflammation and are looking for a natural solution, CBD topicals are worth considering. Infused with cannabidiol (CBD), one of the most prominent naturally occurring cannabinoids found in the cannabis plant, these products are applied directly to the skin, offering quick, effective relief from physical discomfort.
Topical CBD creams come in various formulas and are often crafted with additional ingredients, like aloe vera and lavender oil, for skin health benefits. With so many options available, finding the best CBD oil cream for your needs can be challenging. To help you find the perfect one, we’ve curated a list of the five best options on the market.
Keep reading to learn more about our selections and how CBD topicals can reduce pain, ease inflammation, and improve mobility.
Summary of the Best CBD Creams
- Best Overall: Aspen Green Relief Full-Spectrum CBD Cream
- Best for Moderate Pain: R&R CBD Pain Creams
- Best for Inflammation: CBDfx CBG + CBD Lotion for Muscle & Joint: Heating Formula
- Best Broad-Spectrum Cream: Koi Naturals CBD Balm
- Best for Fast Effects: Medterra Pain Relief Cream
Best CBD Creams - Brand Reviews
1. Best Overall: Aspen Green Relief Full-Spectrum CBD Cream

What we love:
Harnessing the benefits of the complete range of cannabis compounds for natural pain relief, Aspen Green Relief Full-Spectrum CBD Cream snagged the top spot on our list. This physician-formulated cream is crafted with hemp seed oil and other moisturizing ingredients to hydrate dry skin while easing pain and inflammation. The inclusion of tea tree oil and menthol provides a cooling sensation and additional relief from discomfort in joints and muscles. Unlike many CBD topicals, this cream doesn’t contain artificial preservatives, synthetic ingredients, or plasticizers.
This topical cream is made with organic, vegan, non-GMO, and sustainable ingredients to align with various lifestyles. It’s produced using an eco-friendly, non-toxic extraction process, producing exceptional quality. Aspen Green adheres to current Good Manufacturing Practices (cGMP) and produces its goods in an FDA-registered facility.
Its water-based formula goes on smoothly, absorbs quickly, and doesn't leave a sticky or oily residue. This product contains less than 0.3% THC based on dry weight, making it federally legal according to the Farm Bill of 2018. It’s made with food-grade ingredients, including USDA-certified organic CBD. Plus, the brand offers a satisfaction guarantee so you can purchase with peace of mind.
Customers say this product is great for alleviating various types of pain, including joint discomfort and arthritis pain. One satisfied reviewer even called it a “miracle in a jar.” Buyers say a little bit of this cream goes a long way, and the effects last several hours.
Pros:
- Made with full-spectrum CBD for enhanced effects
- 100% organic and natural ingredients
- Certificate of Analysis available on website
- USA-made and physician-formulated
Cons:
- Not suitable for those avoiding THC
Specs:
- CBD type: Full-spectrum
- Size: 2 ounces per jar
- Strength: 33 mg THC and 1,000 mg CBD per jar
- Scent(s): Unspecified
Learn more about Aspen Green Relief Full-Spectrum CBD Cream today!
2. Best for Moderate Pain: R&R CBD Pain Creams

What we love:
Whether you’re struggling with persistent pain or a temporary workout injury, R&R CBD Pain Creams have you covered. Boasting an extra-strength formula, this product works hard to deliver the combined therapeutic benefits of CBD,other cannabinoids, and other powerful naturals to targeted areas. This is one of the best options for those who want a potent treatment for moderate discomfort.
This CBD lotion contains USDA Organic full—spectrum CBD—which includes a complete range of cannabinoids like THC, CBC, CBG, and CBN—as well as shea butter, jojoba seed oil, baobab seed oil, and other naturally occurring ingredients. Cannabis compounds, jojoba oil, arnica, and MSM work in synergy to reduce inflammation and relieve pain, while additions like shea butter hydrate dry skin. R&R creates some of the highest potency creams we’ve seen on the market, including a 5000mg strength for maximum relief.
By using this product daily, users can tap into the enhanced cumulative impact of CBD, leading to a noticeable decrease in pain and inflammation and an increase in physical capabilities. This formula reduces pain signals in the brain and speeds up your body's natural ability to heal and recover from injuries without the laundry list of side effects that often accompany pharmaceutical pain medications.
Like all of R&R’s products, this cream is subjected to rigorous third-party lab testing to confirm its purity, potency, and safety. The brand invites prospective buyers to view the lab reports for all its goods on its website. Plus, all purchases are backed by a 60-day satisfaction guarantee for your reassurance. At their price per mg of CBD, they are also one of the highest value creams on the market.
Customers love how quickly and well this product works to alleviate pain and discomfort. They appreciate that the cream doesn’t leave any greasy residue and is easy to apply. Buyers say this topical effectively treats various types of pain, ranging from sciatica to sprains. Some even report improved sleep quality when using it.
Pros:
- Third-party lab tested with transparent results
- Made natural ingredients, including organic hemp
- Therapeutic benefits build over time
- Available in three potency choices
Cons:
- Must be used daily for optimal results
Specs:
- CBD type: Full-spectrum
- Size: 2.5 ounces per tube
- Strength: 1,000 mg, 2,500 mg, or 5,000 mg CBD per tube
- Scent(s): Fragrance and Dye Free
Learn more about R&R CBD Pain Creams today!
3. Best for Inflammation: CBDfx CBG + CBD Lotion for Muscle & Joint: Heating Formula

What we love:
CBDfx offers some of the most innovative CBD creams on the market, including its CBG + CBD Lotion for Muscle & Joint: Heating Formula. This CBD cream offers potent pain alleviation using only natural ingredients, featuring a perfectly balanced blend of broad-spectrum CBD and CBG—as well as white willow bark, caffeine, and tea tree oil. The included camphor provides a heating sensation to soothe sore muscles and ease joint pain.
This product also contains vanillin, the primary flavor compound in vanilla. This substance has powerful antioxidant and anti-inflammatory properties, further contributing to the cream’s overall benefits. Crafted in the USA with organic hemp, this topical marvel is vegan-friendly and cruelty-free.
Made without the additives, fillers, and chemicals often found in sports creams, this product is toxin- and solvent-free and can be reapplied as needed. It goes on smoothly and absorbs quickly, delivering speedy, targeted pain relief to the affected area. It comes in a convenient, travel-friendly bottle with a pump top for easy application, and the included lid prevents and contains potential messes. It’s covered by a 60-day satisfaction guarantee and has been carefully lab-tested to confirm potency and safety.
Many customers say this is one of the best CBD creams they’ve ever used. They report experiencing deep relief from hip pain, carpal tunnel syndrome, arthritis, backaches, and sports-related injuries. Buyers appreciate the high concentrations of CBG and CBD per bottle and the soothing effects of camphor.
Pros:
- Offers deep, penetrating relief of various types of pain
- Contains a balanced ratio of CBD and CBG
- Broad-spectrum formula produces synergistic effects
- Covered by a 60-day guarantee
Cons:
- May not be suitable for those with sensitive skin
Specs:
- CBD type: Broad-spectrum
- Size: 1.7 ounces per bottle
- Strength: 1,000 mg CGB and 1,000 mg CBD per container or 3,000 mg CBG and 3,000 mg CBD per container
- Scent(s): Unspecified
Learn more about CBDfx CBG + CBD Lotion for Muscle & Joint Heating Formula today!
4. Best Broad-Spectrum Cream: Koi Naturals CBD Balm

What we love:
If you’re looking for a broad-spectrum CBD pain cream to soothe aches and enhance skin health, we recommend trying Koi Naturals CBD Balm. With three potency options, finding the perfect fit for your needs is easy. In addition to a hefty dose of CBD, this product is formulated with natural essential oils, including lavender oil and aloe vera, to hydrate, soften, and smooth dry skin.
This balm gently soothes muscle pain and aches, giving users a refreshed, relaxed feel without side effects or greasy residue. Whether you’re struggling with acute or chronic pain, this topical treatment offers quick, effective, targeted relief. It comes in two sizes: a full-size container ideal for at-home use and a smaller container that can be kept in your gym bag or travel bag for effortless on-the-go use.
Koi is committed to quality, transparency, and customer satisfaction. As such, it has all of its products third-party lab-tested and makes the Certificates of Analysis easily accessible on its website. This cream is made with USA-grown hemp and is infused with a pleasant yet subtle scent. The balm melts into the skin easily, offering easy application and fast absorption.
Customers love how easy this CBD balm is to apply and how quickly it works. They say it rubs right into the skin without leaving a mess behind. The essential oils are penetrating and soothing and the fragrance is pleasant without being overpowering. Reviewers say this CBD cream has helped them with leg, ankle, muscle, back, and joint pain. They also report softer, smoother skin after use. Buyers with sensitive skin say this balm doesn’t irritate their skin.
Pros:
- No sticky or oily residue
- Third-party lab-tested with accessible results
- Available in multiple sizes and potencies
- Delivers fast and effective relief
Cons:
- May not be potent enough for severe pain
Specs:
- CBD type: Broad-spectrum
- Size: 1.7 ounces or 0.5 ounces per container
- Strength: 150 mg, 500 mg, or 1,000 mg CBD per container
- Scent(s): Unspecified
Learn more about Koi Naturals CBD Balm today!
5. Best for Fast Effects: Medterra Pain Relief Cream

What we love:
Medterra Pain Relief Cream is an outstanding option for fast-acting, long-lasting pain relief without side effects. Leveraging the therapeutic benefits of hemp, menthol, and botanical ingredients, this product is highly versatile and can handle all your pain issues, including muscle aches, joint pain, and post-workout soreness.
This CBD pain cream contains various natural ingredients, including aloe vera, arnica, shea butter, hemp extract, jojoba oil, menthol, and numerous others, to deliver a cooling sensation and soothing relief. It’s available in two potency options, so you can choose the one that’s best for your pain management needs.
This cream comes in a portable bottle with a pump top and a lid, making it perfect for convenient on-the-go use. Its smooth consistency allows for effortless application and optimal absorption. It has been thoroughly lab-tested by an independent lab. With a full commitment to transparency and safety, Medterra makes its Certificates of Analysis available on its website and also includes a QR code on every bottle that links back to its lab results. Plus, it’s certified by the U.S. Hemp Authority, further demonstrating its credibility.
This formula doesn’t contain THC, making it ideal for those looking to avoid the popular cannabinoid. It’s made with USA-grown hemp and is vegan-friendly, gluten-free, and non-GMO. Thanks to the brand’s 30-day satisfaction guarantee, you can try this topical CBD product risk-free and receive a full refund if unsatisfied.
Many reviewers use this product daily to relieve post-surgical or chronic pain, while others apply it after strenuous workouts. Buyers love the convenience, portability, and ease of application this cream offers, as well as the easy access to lab results.
Pros:
- Easy application and sustained results
- Made with high-quality, USA-grown hemp
- Portable container for easy on-the-go use
- Gluten-free, non-GMO, and vegan-friendly
Cons:
- Not suitable for those who prefer CBD topicals containing THC
Specs:
- CBD type: Broad-spectrum
- Size: 1.7 ounces per container
- Strength: 500 mg or 1,000 mg hemp per container
- Scent(s): Unspecified
Learn more about Medterra Pain Relief Cream today!
How We Picked the Best CBD Creams
Not all CBD products are the same. When choosing products to feature on our list of the best CBD creams available, we looked at a variety of factors to ensure each product is safe, effective, and of the highest quality. Some of the factors we considered include the following.
Type of CBD
The type of CBD extract used in a topical formula plays a large role in its effects. We focused on products featuring broad-spectrum and full-spectrum CBD, offering the most potent, comprehensive benefits.
Supportive Added Ingredients
Some CBD products contain other ingredients, like menthol, that offer additional pain-relieving, anti-inflammatory effects. We prioritized these products, as well as those formulated with skin-enhancing ingredients like essential fatty acids, aloe vera, shea butter, and lavender oil.
Customer Reviews
We examined customer reviews to determine which topical CBD products are most effective. We paid attention to recurring praises and complaints. All the products showcased above are backed by plenty of positive reviews attesting to their efficacy in alleviating muscle aches, joint pain, and skin conditions.
How To Find the Best CBD Cream for You
With so many different types of topical CBD products on the market, it can be difficult to pinpoint the best CBD cream for your specific needs. Considering the following factors will help you narrow down your options and find one that aligns with your wellness goals:
Allergies and Sensitivities
Before purchasing a topical product infused with CBD oil, check the description to ensure the cream doesn’t contain any potentially problematic ingredients that may trigger allergies or sensitivities. For example, if you have sensitive skin, make sure the product you choose is suitable for sensitive skin; if you’re allergic to coconut, look for CBD topicals that don’t contain coconut oil or other derivatives.
Pain Type
While CBD creams generally aim to alleviate pain, some formulas are better suited to ease certain types of pain than others. That said, checking product descriptions and reviews can help you find the most suitable cream for your pain. If you have arthritis, look for a joint cream that promises to reduce joint pain and inflammation. If you’re struggling with mild or acute pain, look for CBD topicals that reviewers say offer effective acute pain relief.
CBD Topical Strength
The concentrations of CBD oil in CBD topicals vary from one product to another. Low-potency formulas can be great for minor aches and pains. However, they may be less effective for treating severe or chronic pain. For those with severe pain, it may be beneficial to consider a higher-strength product. Consider the intensity and frequency of your pain when choosing a CBD topical formula or joint cream to ensure it’ll offer sufficient relief.
Brand Reputation
Always purchase your CBD topicals from reputable brands. The best vendors have their products third-party lab-tested to verify they contain the advertised concentrations of CBD and other ingredients and are free from harmful contaminants. Choose brands committed to transparency and allow you to review their Certificates of Analysis. Offering a money-back guarantee is another indication that a retailer is reputable.
Types of CBD
CBD lotion and other topical CBD products contain one of three different types of CBD oils: full-spectrum, broad-spectrum, or isolate. Below, we’ve outlined the properties of each CBD type.
Full-Spectrum CBD
Full-spectrum CBD topicals contain all compounds of the cannabis plant, including trace amounts of THC. These topical products don’t cause psychoactive effects or positive drug tests. Many users prefer full-spectrum formulas, as their wider range of compounds can provide enhanced benefits. This is known as the entourage effect.
Broad-Spectrum CBD
Broad-spectrum topical products contain all of the compounds of the cannabis plant except THC. Broad-spectrum CBD is put through a special process to remove all traces of THC. The result is a formula that offers synergistic effects while remaining suitable for users who prefer to avoid THC.
CBD Isolate
CBD isolate is the purest form of CBD. It doesn’t contain any other plant compounds. While it doesn’t produce an entourage effect, it can help treat mild discomfort.
Other Types of CBD Products
There’s no shortage of CBD products on the market today. If topicals aren’t your first choice, many other types of CBD products can potentially help ease joint and muscle aches as well as other types of pain. Some of the other CBD product forms you may be interested in include the following:
CBD Tinctures and CBD Oil
CBD tinctures and CBD oils are liquid concentrates. They can be taken sublingually (under the tongue) for ultra-fast absorption and speedy results or added to foods and beverages. Many users appreciate the versatility and dosing precision of these products.
CBD Edibles
CBD edibles, like gummies, are consumed orally and come in different flavors. They contain pre-calculated amounts of CBD, are easy to chew and swallow, and are discreet, making them convenient for on-the-go use.
CBD Capsules
Slightly less convenient than a gummy, a CBD capsule is filled with a pre-measured dose of CBD oil and can be a good option for those who value discretion or are trying to bypass the taste of CBD oil. Simply swallow a capsule with a sip of water, and you should start feeling the effects within an hour.
CBD Vape Juices
Another way to reap the benefits of CBD is by vaping. CBD vapes come in various flavors and are known for their quick-acting effects. However, they may not be the best choice for users with sensitive lungs or respiratory conditions.
Benefits of CBD Cream
Ideal for localized pain relief, CBD creams are applied topically and work by interacting with cannabinoid receptors located throughout the body to reduce pain sensation and regulate pain perception and certain immune responses, like inflammation. The following are some of the potential benefits these products offer:
- Pain relief: Topical CBD products are thought to have pain-relieving, anti-inflammatory properties. They can help reduce muscle discomfort, tendons, ligaments, and other tissues and aid muscle recovery after overuse, injury, or extensive exercise.
- Improved mobility: Inflammation is the immune system’s natural reaction to cell damage. CBD interacts with the immune system, reducing inflammation and the resulting pain. By minimizing pain and swelling, CBD cream can make it easier for users to move around, potentially improving quality of life.
- Healthier skin: CBD cream products are often formulated with beneficial ingredients—like aloe barbadensis leaf juice, coconut oil, hemp seed oil, and olive oil—that can soften and hydrate the skin. Some CBD topicals can help treat skin irritation, acne, dry skin, and eczema.
Potential Side Effects of CBD Topicals
Many people use topical CBD products without experiencing adverse effects. However, there are some potential side effects to be aware of, including:
- Skin irritation (e.g., contact dermatitis, rash, etc.)
- Dry mouth
- Diarrhea and vomiting
- Fatigue and drowsiness
- Allergic reactions
Also, CBD topicals can interact with other medications you may be taking, such as anticoagulants, stimulants, and heartburn medications. Before using CBD topicals or other cannabis products, consider whether CBD interacts with medications or supplements you’re taking, and consult your healthcare provider to discuss safety concerns.
FAQ
Is CBD cream safe?
For most people, CBD cream for pain is generally safe. You can take steps to help ensure safety when using CBD lotions. Purchase products that have been third-party tested and confirmed free from contaminants. (Review the product’s Certificate of Analysis to verify its safety for yourself.) Always use the product according to the manufacturer’s directions. If you have allergies or sensitivities, check the ingredients label to ensure your chosen product doesn’t contain any ingredients that may disagree with you. Also, if you’re taking medication, it’s a good idea to check with your doctor to make sure CBD won’t cause any unwanted drug interactions.
Is CBD cream legal?
As per the 2018 Farm Bill, CBD is federally legal if it’s hemp-derived and doesn’t exceed 0.3% THC based on dry weight. Although CBD is legal on a federal level, it may not be legal in some states. Be sure to check your local regulations to confirm legality before buying, using, or selling CBD products.
How much CBD cream should I use?
This depends on the potency of your CBD cream, the intensity of your pain, and the effects you desire. Manufacturers typically provide instructions on how to apply CBD cream and how much to use. We recommend adhering to these directions for optimal results unless otherwise instructed by your doctor.
How fast does CBD cream work?
How quickly you experience effects may vary depending on the specific topical CBD product and its formula. High-potency and full-spectrum options tend to kick in faster than lower-strength and isolate formulas. Generally, most people start feeling the pain-relieving effects within an hour or less of application. Factors such as the type of CBD used, potency, and individual factors all play a role in the onset and duration of effects.
Does CBD cream have side effects?
CBD cream can provide pain relief and other wellness benefits, but there are also some risks and side effects to consider. As with any topical product, you should check the ingredients to ensure you’re not allergic to them. If you have sensitive skin, consider any additives in the product that may cause irritation. Some of the potential side effects associated with the use of CBD cream include:
CBD cream can interact with medications and supplements. Before adding it to your wellness routine, verify that your current prescription or over-the-counter medications are safe to use with the CBD product.
Some people may suffer skin reactions, including irritation, reddening, tightness, or a rash. If you have sensitive skin, ensure the product you choose suits you.
Some users experience gastrointestinal discomfort, including diarrhea or nausea, after using CBD cream. If you notice these side effects, discontinue use and consult your healthcare provider for further guidance.
CBD can reduce saliva production, leading to dry mouth in some users. This can be easily addressed by sipping water after use.
Lastly, some CBD topicals, especially full-spectrum formulas, can cause fatigue or drowsiness. If this occurs, try switching to a broad-spectrum or isolate product.
Conclusion
For those who struggle with joint pain, sore muscles, backaches, or other types of physical discomfort, the right CBD cream can be life-changing and offer significant pain relief. These CBD pain creams are formulated with natural ingredients and interact with the body’s nervous system to regulate pain perception and response.
For many people, these topical products provide a fast, natural pain management solution without the side effects often associated with pain medications. High-quality topical CBD products can ease pain and inflammation resulting from injuries, intense workouts, or health conditions. If you’re ready to say goodbye to pain and swelling and hello to enhanced mobility and improved quality of life, check out these topical CBD options today.
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